Localized grain-leather plaque in urticaria pigmentosa – An unusual coexistence of dual morphology

oleh: Sanjiv Choudhary, Ankita Srivastava, Deepti Joshi, Santosh Tummudi

Format: Article
Diterbitkan: Wolters Kluwer Medknow Publications 2020-01-01

Deskripsi

Urticaria pigmentosa (UP), the most common variant of cutaneous mastocytosis (CM), is characterized by hyperpigmented, brownish macules and patches, with positive Darier's sign. Diffuse cutaneous mastocytosis (DCM), is a rare variant of CM, characterized by diffuse infiltration of the skin by mast cells (MCs), resulting in a typical grain-leather appearance. Blistering is commonly seen in infants with CM but it is not specific for any variant of CM. Herein, we report a case of a 5-month-old male infant who presented with recurrent bullous lesions and hyperpigmented, brownish patches with intervening normal skin suggestive of UP, as well as a single, localized plaque with grain-leather appearance, thereby exhibiting an interesting dual morphology.