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Motivated by the Gaussian symplectic ensemble, Mehta and Wang evaluated the $n×n$ determinant $\det ((a+j-i)Γ (b+j+i))$ in 2000. When $a=0$, Ciucu and Krattenthaler computed the associated Pfaffian $\mathrm{Pf}((j-i)Γ (b+j+i))$ with an application to the two dimensional dimer system in 2011. Recently we have generalized the latter Pfaffian formula with a $q$-analogue by replacing the Gamma function by the moment sequence of the little $q$-Jacobi polynomials. On the other hand, Nishizawa has found a q-analogue of the Mehta–Wang formula. Our purpose is to generalize both the Mehta-Wang and Nishizawa formulae by using the moment sequence of the little $q$-Jacobi polynomials. It turns out that the corresponding determinant can be evaluated explicitly in terms of the Askey-Wilson polynomials.