Carbene footprinting accurately maps binding sites in protein–ligand and protein–protein interactions
oleh: Lucio Manzi, Andrew S. Barrow, Daniel Scott, Robert Layfield, Timothy G. Wright, John E. Moses, Neil J. Oldham
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2016-11-01 |
Deskripsi
Mapping protein-ligand interactions is fundamental to advance the understanding of cellular processes and to develop drug discovery strategies. Here, the authors present a photo-activated probe that allows highly efficient labelling and identification of protein binding sites using mass spectrometry.