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Yuan Li,1 Biru Luo2 1Nursing Department, West China Second University Hospital, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University, Ministry of Education, West China School of Nursing, Sichuan University, Chengdu, People’s Republic of China; 2Nursing Department, West China Second University Hospital, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University, Ministry of Education, Sichuan, Chengdu, People’s Republic of ChinaCorrespondence: Biru Luo Tel +86-1 818 060 9180Email Biruluo_wcsuh@outlook.comAbstract: The ongoing coronavirus disease has heightened enormous concern in the global community. China implemented extraordinary public health measures to take the major transmission hotspots under control at great socioeconomic cost. Frontline health-care workers have shown their commitment and accountability in the fight against the epidemic outbreak. This commentary acknowledges their contribution and offers important insights for devising future strategies in enhancing preparedness and response competencies among the health-care workforce to manage future epidemic events.Keywords: COVID-19, coronavirus, health-care worker, outbreak, preparedness and response