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Target specific drug design has attracted much attention in drug discovery. But, it is a great challenge to efficiently explore the target-focused chemical space. Fragment-based drug design (FBDD) has shown its potential to do this thing. In this study, we introduced a deep learning-based fragment linking method, namely SyntaLinker-Hybrid, for target specific molecular generation. By carrying out transfer learning and fragment hybridization, this method allows to generate a great number of linker fragments to assemble given terminal fragments into the molecules with target specificity. This work demonstrates that the method has the capacity to generate target specific structures for various targets. We believe that its application could be extended to a broader target scope.