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Systemic lupus erythematosus is a prototype systemic autoimmune disease with varied presentations. Cutaneous and musculoskeletal manifestations are common clinical presentations. Severe disease activity results in multiorgan involvement among which kidneys are commonly affected in first two years after the onset of disease. Normally nonspecific cutaneous manifestations correlate with disease activity. Among such cutaneous manifestations Steven Johnsons and toxic epidermal necrolysis, which were associated with high mortality in lupus, were rarely reported. Periodic assessment of disease activity and severity are important to minimize high mortality and morbidity associated with this disease.