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The article provides an analysis of using medications in children’s oncohematological department in Tomsk in 2008. Over that period 52 children aged from 6 months to 18 years were treated (with an acute lymphatic leukaemia, lymphogranulomatosis, non Hodgkin lymphom, acute and chronic myeloblastic leukemia, etc.). According to АВС/VEN analysis, 79,9% of funds was spent on acquisition of 11 group A medications, 15,1% — on group B medications, 5% — on group C medications. Vital medications (V) accounted for 79,4%, essential medications (Е) — 14,7%, non-essential medications (N) — 5,9%. The authors examined the toxicity of vincristine depending on manufacturers. Key words: children, malignant blood diseases, ABC/VEN analysis, vincristine, neurotoxicity. (Pediatric Pharmacology. – 2010; 7(3):14-16)