Modular fluorescence complementation sensors for live cell detection of epigenetic signals at endogenous genomic sites
oleh: Cristiana Lungu, Sabine Pinter, Julian Broche, Philipp Rathert, Albert Jeltsch
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2017-09-01 |
Deskripsi
Tools for imaging epigenetic modifications can shed light on the regulation of epigenetic processes. Here, the authors present a fluorescence complementation approach for detection of DNA and histone methylation at endogenous genomic sites allowing following of dynamic changes of these marks by live-cell microscopy.