Automatic classification and segmentation of single-molecule fluorescence time traces with deep learning

oleh: Jieming Li, Leyou Zhang, Alexander Johnson-Buck, Nils G. Walter

Format: Article
Diterbitkan: Nature Portfolio 2020-11-01

Deskripsi

Traces from single-molecule fluorescence microscopy (SMFM) experiments exhibit photophysical artifacts that typically make analysis time-consuming. Here, the authors have developed an easily accessible software, AutoSiM, for two distinct applications of deep learning to the efficient processing of SMFM time traces.