1,2,3,4-Tetrahydro-1,4-methanonaphthalene-2,3-diol
oleh: Jian Xu, Hao Xu, Ji-cai Quan, Fei Sha, Cheng Yao
| Format: | Article |
|---|---|
| Diterbitkan: | International Union of Crystallography 2009-01-01 |
Deskripsi
The title compound, C11H12O2, is an intermediate in the synthesis of Varenicline, a nicotinic receptor partial agonist used to treat smoking addiction. In the crystal structure, there is an intramolecular O—H...O hydrogen bond that generates an S(5) ring motif. Intermolecular O—H...O hydrogen bonds form centrosymmetric dimers and also link these dimers into chains along the a axis.