Electron transfer-triggered imaging of EGFR signaling activity
oleh: Jie Tan, Hao Li, Cailing Ji, Lei Zhang, Chenxuan Zhao, Liming Tang, Caixin Zhang, Zhijun Sun, Weihong Tan, Quan Yuan
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-02-01 |
Deskripsi
Here, the authors design a nanoprobe for in vivo imaging of electronic transfer, consisting of a ferrocene-DNA polymer to transfer electrons to luminescent nanoparticles, changing their optical signal. Using this probe, they map activation of EGFR signalling during tumour treatment.