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What Can Gamma Delta T Cells Contribute to an HIV Cure?
oleh: Jennifer A. Juno, Stephen J. Kent, Stephen J. Kent, Stephen J. Kent
Format: | Article |
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Diterbitkan: | Frontiers Media S.A. 2020-05-01 |
Deskripsi
Elimination of the latent HIV reservoir remains a major barrier to achieving an HIV cure. In this review, we discuss the cytolytic nature of human gamma delta T cells and highlight the emerging evidence that they can target and eliminate HIV-infected T cells. Based on observations from human clinical trials assessing gamma delta immunotherapy in oncology, we suggest key questions and research priorities for the study of these unique T cells in HIV cure research.