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This article is aimed at people who suffer from muscular dystrophy or amyotrophic lateral sclerosis. A webcam captures images of the user’s head, and the computer then processes these images to calculate and transform the swinging direction and distance of the user’s head into the position of the mouse cursor and into the action of clicking the mouse. To accurately and quickly recognize these features, this article used a round sticker with a diameter of 1 cm as an identification label, which is stuck on the user’s forehead. After the webcam captures the images, the program can recognize the positions of the identification label and move the mouse cursor. Through Windows API, this article determined the user’s intention and action of clicking the mouse on the basis of a series of movements to control the mouse cursor. As confirmed by the experimental results, the proposed assisted computer entry device for muscular atrophy patients is applicable and gives good results for the e-book reading program, use of the web browser, and the execution of the application software and mini-games developed by this system structure.