Cep55 promotes cytokinesis of neural progenitors but is dispensable for most mammalian cell divisions
oleh: Antonio Tedeschi, Jorge Almagro, Matthew J. Renshaw, Hendrik A. Messal, Axel Behrens, Mark Petronczki
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2020-04-01 |
Deskripsi
In mammalian cell lines, Cep55 protein recruits the endosomal sorting complex required for transport (ESCRT) and promotes the completion of cell division. Here, the authors show that Cep55-knockout mice are viable and primary fibroblasts cultured in vitro divide in a Cep55 and ESCRT-independent way.