Molecular mechanisms and topological consequences of drastic chromosomal rearrangements of muntjac deer
oleh: Yuan Yin, Huizhong Fan, Botong Zhou, Yibo Hu, Guangyi Fan, Jinhuan Wang, Fan Zhou, Wenhui Nie, Chenzhou Zhang, Lin Liu, Zhenyu Zhong, Wenbo Zhu, Guichun Liu, Zeshan Lin, Chang Liu, Jiong Zhou, Guangping Huang, Zihe Li, Jianping Yu, Yaolei Zhang, Yue Yang, Bingzhao Zhuo, Baowei Zhang, Jiang Chang, Haiyuan Qian, Yingmei Peng, Xianqing Chen, Lei Chen, Zhipeng Li, Qi Zhou, Wen Wang, Fuwen Wei
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-11-01 |
Deskripsi
Muntjac deer underwent rapid species radiation and dramatic chromosome fusions within a short period of time. Here the authors reveal that repeat sequences likely mediated illegitimate recombination to result in chromosome fusions and that 3D chromatin architecture around fusion sites have no significant change, while significant interactions across fusion sites were gradually established after speciation.