Active intermixing of indirect and direct neurons builds the striatal mosaic
oleh: Andrea Tinterri, Fabien Menardy, Marco A. Diana, Ludmilla Lokmane, Maryama Keita, Fanny Coulpier, Sophie Lemoine, Caroline Mailhes, Benjamin Mathieu, Paloma Merchan-Sala, Kenneth Campbell, Ildiko Gyory, Rudolf Grosschedl, Daniela Popa, Sonia Garel
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2018-11-01 |
Deskripsi
Striatal projection neurons exist as two distinct classes and are anatomically mixed in the brain. Here, Tinterri and colleagues show the developmental mechanism of this cellular mosaicism that relies on an intrinsic transcription factor for cell type specification and intermixed cellular migration.