A distinct holoenzyme organization for two-subunit pyruvate carboxylase
oleh: Philip H. Choi, Jeanyoung Jo, Yu-Cheng Lin, Min-Han Lin, Chi-Yuan Chou, Lars E. P. Dietrich, Liang Tong
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2016-10-01 |
Deskripsi
Pyruvate carboxylases are homotetrameric enzymes in eukaryotes and most bacteria. Here, the authors report the structure of an unusual two-subunit form of the enzyme from the Gram-negative bacterium Methylobacillus flagellates, revealing an unexpected α2β4stoichiometry.