Multidrug-resistant Tuberculosis Detection, Latvia

oleh: Girts Skenders, Alicia M. Fry, Inga Prokopovica, Silvija Greckoseja, Lonija Broka, Beverly Metchock, Timothy H. Holtz, Charles D. Wells, Vaira Leimane

Format: Article
Diterbitkan: Centers for Disease Control and Prevention 2005-09-01

Deskripsi

To improve multidrug-resistant tuberculosis (MDR-TB) detection, we successfully introduced the rpoB gene mutation line probe assay into the national laboratory in Latvia, a country with epidemic MDR-TB. The assay detected rifampin resistance with 91% sensitivity and 96% specificity within 1 to 5 days (vs. 12–47 days for BACTEC).