Metabolome and proteome analyses reveal transcriptional misregulation in glycolysis of engineered E. coli
oleh: Chun-Ying Wang, Martin Lempp, Niklas Farke, Stefano Donati, Timo Glatter, Hannes Link
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-08-01 |
Deskripsi
Synthetic pathways represent a metabolic burden on host cells. Here the authors engineer Cra-binding sites to prevent misregulation in glycerol and carotenoid overproducing E. coli strains.