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COVID-19 infection recently broke out around the world affecting more than 2 million people. This is written in the context of importance of physical therapy interventions for clearing the secretion in the lungs during viral infections. In the case of lower respiratory tract infection the volume of thick secretion increases, that compromise the airway functioning. Covid-19 had affected the elderly and individuals with compromised immune systems, previous respiratory diseases like COPD, chronic bronchitis, or mucous-related issues of increased or decreased secretions. These secretions can cause a decreased area of ventilation. Therefore, lungs should be drained to increase pulmonary functions with different techniques known as Airway Clearance Techniques (ACT). These techniques can be passive including percussion, vibrations, and postural drainage, and others include Autogenic drainage, positive pressure expiratory techniques, and active cycle of breathing (ACB). The lungs can be cleared using postural drainage techniques. These techniques are non-invasive procedures and can help to improve respiratory functions, gaseous exchange, increased pulmonary functions, and retained mucus removal. Early rehabilitation programs in acute phases of the disease are suggested to prevent such complications and promote early recovery. The working professionals who are treating victims should follow the infection control protocols and position themselves at maximum distance. The use of precautionary measures, including masks, gloves, fluid-resistant gowns, and face shields, should be followed. Keys Words: Autogenic Drainage, Chest physiotherapy, Corona Viruses, COVID-19, Physical therapy, Postural drainage, Viral Infections