The emergence of piRNAs against transposon invasion to preserve mammalian genome integrity
oleh: Christina Ernst, Duncan T. Odom, Claudia Kutter
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2017-11-01 |
Deskripsi
Transposable elements can be activated during germ cell maturation, potentially leading to genome instability and rewiring of the genetic circuitry. In this review, the authors discuss how the piRNA machinery suppresses these elements to ensure accurate spermatogenesis.