Waffle Method: A general and flexible approach for improving throughput in FIB-milling

oleh: Kotaro Kelley, Ashleigh M. Raczkowski, Oleg Klykov, Pattana Jaroenlak, Daija Bobe, Mykhailo Kopylov, Edward T. Eng, Gira Bhabha, Clinton S. Potter, Bridget Carragher, Alex J. Noble

Format: Article
Diterbitkan: Nature Portfolio 2022-04-01

Deskripsi

Here the authors describe the Waffle Method, aimed at increasing the throughput of and solves several challenges present in cryo-FIB/SEM sample preparation for cryo-ET analysis — the highest-resolution method for obtaining 3D views of native biological specimens in-situ.