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<strong>BACKGROUND:</strong> We aimed to evaluate subepicardial and subendocardial left ventricular (LV)<br />functions in patients with single coronary artery lesion at an early stage after percutaneous<br />coronary intervention (PCI).<br /><strong>METHODS:</strong> Patients with left anterior descending (LAD) lesion (n = 40) were evaluated.<br />Subjects underwent PCI and at least one coronary stent was placed. Before and one month after<br />PCI, patients underwent echocardiography. The ordinary Doppler indicators including E wave<br />deceleration time, A velocity and E velocity as well as the pulsed-wave tissue Doppler imaging<br />(PW-TDI) parameters (Aa, Ea and Sa velocity) were measured. The findings before and after<br />intervention were compared.<br /><strong>RESULTS:</strong> E wave deceleration time was the only factor that significantly improved in ordinary<br />Doppler and other parameters such as A velocity and E velocity did not show any changes.<br />Among TDI parameters, Aa velocity and Ea velocity in septum area improved significantly but<br />despite an increase in Sa velocity in septum, it was not statistically significant. Ea velocity<br />significantly improved in lateral area but Aa and Sa velocity insignificantly increased.<br /><strong>CONCLUSION: </strong>In patients with coronary artery disease, the systolic and diastolic function is<br />impaired. It is simply diagnosable by TDI. Although the systolic function impairment is<br />remained after PCI, the diastolic function considerable improved after angioplasty. Our study<br />showed that diastolic function of left ventricle improved over time. In contrast with other<br />studies, in this study, Aa velocity significantly improved one month after revascularization.<br /><strong>Keywords</strong>: Angioplasty, Percutaneous Coronary, Echocardiography, Doppler, Tissue Doppler