Dual catalysis for enantioselective convergent synthesis of enantiopure vicinal amino alcohols
oleh: Chen-Xi Ye, Yared Yohannes Melcamu, Heng-Hui Li, Jiang-Tao Cheng, Tian-Tian Zhang, Yuan-Ping Ruan, Xiao Zheng, Xin Lu, Pei-Qiang Huang
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2018-01-01 |
Deskripsi
Chiral vicinal amino alcohols are found in many bioactive compounds and may serve as chiral ligands. Here, the authors report a photocatalytic enantioselective cross-coupling of nitrones with aromatic aldehydes with a chiral ligand-coordinated rare earth ion synergistically producing enantiopure vicinal amino alcohols.