Development and Clinical Efficacy Evaluation of Facial Toner Containing <i>Houttuynia cordata</i> Thunb

oleh: Oraphan Anurukvorakun, Sarunpat Numnim

Format: Article
Diterbitkan: MDPI AG 2023-09-01

Deskripsi

The goal of this research was to develop a reliable oil-controlling toner for facial skin with a natural product, <i>Houttuynia cordata</i> Thunb extract (HCE). The developed HCE facial toner showed high stability and had a high satisfaction level. Clinical studies revealed that the sebum value of the skin after using the developed HCE toner for eight weeks decreased (4.6-times lower), which was statistically significant (<i>p</i>-value < 0.05) when compared to the HCE-free toner. The sebum amount on the facial skin after using the HCE toner decreased by approximately two-times compared to the HCE-free toner. In addition, the skin moisture content increased statistically significantly (<i>p</i>-value < 0.05) from the eighth week of treatment compared to the HCE-free toner and was 1.5- and 1.4-times higher for the left and right cheeks, respectively. The average moisture content of the facial skin treated with the HCE toner increased by 2- and 1.4-times compared to the treatment with the HCE-free toner for the left and right cheeks, respectively. Consequently, the HCE toner had anti-sebum and moisturizing efficacy, and the increased reliability of the natural product meant that it could soon be a premium commercial product.