Tissue-resident Eomes+ NK cells are the major innate lymphoid cell population in human infant intestine
oleh: Adrian F. Sagebiel, Fenja Steinert, Sebastian Lunemann, Christian Körner, Renée R. C. E. Schreurs, Marcus Altfeld, Daniel Perez, Konrad Reinshagen, Madeleine J. Bunders
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2019-02-01 |
Deskripsi
Innate lymphoid cells (ILC), including natural killer (NK) cells, are important innate immune regulators. Here the authors show that, in human infant intestines, CD103+Eomes+ NK cells are the predominant ILC population, but are replaced gradually by Eomes+ T cells, while NKp44+ NK cells persist in adult intestines.