The Atg1–kinase complex tethers Atg9-vesicles to initiate autophagy
oleh: Yijian Rao, Marco G. Perna, Benjamin Hofmann, Viola Beier, Thomas Wollert
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2016-01-01 |
Deskripsi
Autophagosome biogenesis is initiated by recruitment of Atg9-vesicles to the phagophore assembly site. Here Rao et al. use a reconstituted in vitrosystem to describe the mechanism by which activation of the Atg1-kinase complex from its constituent parts recruits and tethers Atg9-vesicles.