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Malignant hyperthermia is a rare hypermetabolic pharmacogenetic pathologic disorder of calcium release control in skeletal muscle following exposure to depolarizing muscle relaxants and inhalational anesthetics in general anesthesia. This report describes the case of a 32-year-old man undergoing emergency laparotomy after being shot in the stomach. The patient suffered a malignant hyperthermia attack following the administration of Succinylcholine to induce anesthesia and Isoflurane to maintain anesthesia. Eventually, we were able to treat the patient for malignant hyperthermia successfully.