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Pulmonary Exacerbation of Undiagnosed Toxocariasis in Intensively-Treated High-Risk Neuroblastoma Patients
oleh: Szymon Janczar, Monika Bulas, Justyna Walenciak, Dobromila Baranska, Marek Ussowicz, Wojciech Młynarski, Beata Zalewska-Szewczyk
Format: | Article |
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Diterbitkan: | MDPI AG 2020-10-01 |
Deskripsi
Toxocariasis is one of the most common zoonoses, with high seroprevalence in apparently healthy individuals. Neuroblastoma is an aggressive childhood cancer. The cure rates are improving due to dose-dense chemotherapy, progress in surgical practice, myeloablative therapy with autologous stem cell transplantation, and recently, anti-GD2 immunotherapy. This is associated with a burden of complications, some of which are relatively specific for neuroblastoma treatment. Based on previous reports of <i>Toxocara canis</i> infection in high-risk neuroblastoma patients and cases of pulmonary exacerbation from our center in this disease, we propose that toxocariasis is a specific complication of intensive pediatric cancer treatment and advocate for active surveillance.