Structure and assembly of double-headed Sendai virus nucleocapsids

oleh: Na Zhang, Hong Shan, Mingdong Liu, Tianhao Li, Rui Luo, Liuyan Yang, Lei Qi, Xiaofeng Chu, Xin Su, Rui Wang, Yunhui Liu, Wenzhi Sun, Qing-Tao Shen

Format: Article
Diterbitkan: Nature Portfolio 2021-04-01

Deskripsi

The authors present the reconstruction of the Sendai Virus N-RNA complex at atomic resolution, including the helical part and a clam-shaped joint, resolved to 2.9 and 3.9 Å respectively, via cryo-EM. They also demonstrate the presence of an additional, ring like structural motif stabilising Nprotein interactions.