Recent Advances in Synthetic Bioelastomers

oleh: Wei Tian, Liqun Zhang, Dafu Chen, Quanyong Liu, Xiaochuan Xu, Yan Wu, Rui Shi

Format: Article
Diterbitkan: MDPI AG 2009-09-01

Deskripsi

This article reviews the degradability of chemically synthesized bioelastomers, mainly designed for soft tissue repair. These bioelastomers involve biodegradable polyurethanes, polyphosphazenes, linear and crosslinked poly(ether/ester)s, poly(ε-caprolactone) copolymers, poly(1,3-trimethylene carbonate) and their copolymers, poly(polyol sebacate)s, poly(diol-citrates) and poly(ester amide)s. The in vitro and in vivo degradation mechanisms and impact factors influencing degradation behaviors are discussed. In addition, the molecular designs, synthesis methods, structure properties, mechanical properties, biocompatibility and potential applications of these bioelastomers were also presented.