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Despite a lower estimated rate of cancer incidence in Iran compared to the global average, the trend is unfortunatelyincreasing. This necessitates the implementation of early detection of cancer and targeted therapies to effectively treatvarious types of cancer. Therefore, the 5th “International Royan Cancer Conference: From Bench to Bedside" washeld to focus on critical cancer-related aspects such as gene- and cell therapy, immunotherapy, oligonucleotides incancer treatment, biosensors for detection, and drug delivery. The 2-day conference took place in February 2024 at theRoyan Institute, Tehran. This collaborative effort brought together experts from both basic and clinical research fields.The primary objective of the conference was to address clinical challenges and harness the potential of basic sciencesfor early cancer diagnosis and treatment, with a robust emphasis on ethical considerations. The conference aimedto ensure optimal patient care while advancing scientific understanding in the field and facilitating effective researchcollaborations among researchers and enthusiasts dedicated to combating cancer.