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In Long Term Evolution (LTE) cellular networks, the transmit power control (TPC) mechanism consists of two parts: the open loop (OL) and closed loop. Most cellular networks consider OL/TPC because of its simple implementation and low operation cost. The analysis of OL/TPC parameters is essential for efficient resource management from the cellular operator's viewpoint. In this work, the impact of the OL/TPC parameters is investigated for homogeneous small cells and heterogeneous small‐cell/macrocell network environments. A mathematical model is derived to compute the transmit power at the user equipment, the received power at the eNodeB, the interference in the network, and the received signal‐to‐interference ratio. Using the analytical platform, the effects of the OL/TPC parameters on the system performance in LTE networks are investigated. Numerical results show that, in order to achieve the best performance, it is appropriate to choose αsmall = 1 and Po‐small = –100 dBm in a homogenous small‐cell network. Further, the selections of αsmall = 1 and Po‐small = –100 dBm in the small cells and αmacro = 0.8 and Po‐macro = –100 dBm in the macrocells seem to be suitable for heterogeneous network deployment.