Genomic evolution towards azole resistance in Candida glabrata clinical isolates unveils the importance of CgHxt4/6/7 in azole accumulation
oleh: Mónica Galocha, Romeu Viana, Pedro Pais, Ana Silva-Dias, Mafalda Cavalheiro, Isabel M. Miranda, Mieke Van Ende, Caio S. Souza, Catarina Costa, Joana Branco, Cláudio M. Soares, Patrick Van Dijck, Acácio G. Rodrigues, Miguel C. Teixeira
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-10-01 |
Deskripsi
Mutations in the hexose transporter, CgHXT4/6/7, contribute to increased antifungal (azole) resistance in the fungal pathogen, Candida glabrata, potentially by influencing azole accumulation.