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Objective To analyze the correlation between stage of oral disease and the transformation of children den⁃ tal anxiety in first visit. Methods Children aged 45 to 74 months (13.7～6.2) years old with molar caries in the first visit were selected and divided into three groups: the acute stage group, the non⁃acute stage group, and the conventional exami⁃ nation group. The face version of the modified child dental anxiety scale (MCDASf) was used to evaluate the changes of anxiety before and after treatment. Results The data of correlation among 3 groups about dental anxiety showed a statis⁃ tical difference (c2 = 9.132, P = 0.010). Compared with acute stage group and non⁃acute stage group, a statistical signifi⁃ cance in dental anxiety can be found (P＜0.012 5). There was no correlation between anxiety prognosis and gender (P＞ 0.05). Conclusion The occurrence and transformation of dental anxiety in children varied with different stage of oral disease. Dental anxiety can be improved significantly by appropriate therapy and behavior management.