Surgical Experience from the STASEY Study of Emicizumab Prophylaxis in People with Hemophilia A with Factor VIII Inhibitors
oleh: Giancarlo Castaman, Flora Peyvandi, Johanna A. Kremer Hovinga, Roger E.G. Schutgens, Susan Robson, Katya Moreno, Víctor Jiménez-Yuste
| Format: | Article |
|---|---|
| Diterbitkan: | Georg Thieme Verlag KG 2024-01-01 |
Deskripsi
Background Guidelines surrounding emicizumab prophylaxis and perioperative treatment for people with hemophilia A (PwHA) with factor (F)VIII inhibitors undergoing surgeries are limited. The phase IIIb multicenter, single-arm STASEY study evaluated safety and tolerability of emicizumab prophylaxis in PwHA aged ≥12 years with FVIII inhibitors. This analysis assesses surgeries during study conduct, associated hemophilia medications, and postoperative bleeds (treated and untreated).