Multidrug resistance: The clinical dilemma of refractory Helicobacter pylori infection

oleh: Chia-Jung Kuo, Cheng-Han Lee, Ming-Ling Chang, Cheng-Yu Lin, Wey-Ran Lin, Ming-Yao Su, Cheng-Hsun Chiu, Chi-Nan Tseng, Yu-Shan Wu, Cheng-Tang Chiu, Chih-Ho Lai

Format: Article
Diterbitkan: Elsevier 2021-12-01

Deskripsi

This study investigated the antimicrobial resistance of isolates from patients with refractory Helicobacter pylori. The resistance rate was 34.1% for amoxicillin, 92.7% for clarithromycin, 65.9% for metronidazole, 85.4% for levofloxacin, and 29.3% for rifabutin. Dual resistance to both clarithromycin and levofloxacin was found in 73.2%. The antimicrobial resistance rate of refractory H. pylori was extremely high, which had become a major consideration in therapeutic challenge.