Direct contribution of skeletal muscle mesenchymal progenitors to bone repair

oleh: Anais Julien, Anuya Kanagalingam, Ester Martínez-Sarrà, Jérome Megret, Marine Luka, Mickaël Ménager, Frédéric Relaix, Céline Colnot

Format: Article
Diterbitkan: Nature Portfolio 2021-05-01

Deskripsi

Bone regeneration involves activation of tissue resident stem cells. Here the authors show that mesenchymal progenitors from skeletal muscle mediate the fibrotic response to bone injury and also contribute to bone repair; processes that are impaired when both muscle and bone are injured.