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Abstract Background Typhoid fever can manifest with a variety of gastrointestinal symptoms. However, in the present-day era, gastrointestinal bleeding related to bowel ulceration is becoming increasingly sporadic especially in the urban setting. Case presentation We present a rare case of life-threatening gastrointestinal bleeding from a typhoid ileal ulcer that was successfully managed with endoscopic therapy. Conclusion Though rare, this infective cause of gastrointestinal bleeding should still be considered in differential diagnosis, especially in developing countries.