AKAP5 Keeps L-type Channels and NFAT on Their Toes

oleh: Manuel F. Navedo, Johannes W. Hell

Format: Article
Diterbitkan: Elsevier 2014-06-01

Deskripsi

In this issue of Cell Reports, Murphy et al. and Dittmer et al. present exciting new insight into the regulation of Ca2+ influx via the L-type Ca2+ channel Cav1.2 and how increased Ca2+ influx translates into localized activation of the nuclear transcription factor NFAT upon depolarization in neurons.