A pediatric brain tumor atlas of genes deregulated by somatic genomic rearrangement

oleh: Yiqun Zhang, Fengju Chen, Lawrence A. Donehower, Michael E. Scheurer, Chad J. Creighton

Format: Article
Diterbitkan: Nature Portfolio 2021-02-01

Deskripsi

The global impact of somatic structural variants (SSVs) on gene expression in childhood cancers is unclear. Here, the authors analyse cancer genome and RNA sequencing data of 854 pediatric brain tumours and report a landscape of genes deregulated by SSVs.