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Pathological manifestation of human endogenous retrovirus K in frontotemporal dementia
oleh: Katherine Phan, Ying He, YuHong Fu, Nicolas Dzamko, Surabhi Bhatia, Julian Gold, Dominic Rowe, Yazi D. Ke, Lars M. Ittner, John R. Hodges, Olivier Piguet, Matthew C. Kiernan, Glenda M. Halliday, Woojin Scott Kim
Format: | Article |
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Diterbitkan: | Nature Portfolio 2021-12-01 |
Deskripsi
Phan et al. assess the presence of human endogenous retrovirus K (HERV-K) in the serum and brain samples of individuals with behavioral variant frontotemporal dementia (bvFTD) with TDP-43 pathology, as seen in amyotrophic lateral sclerosis. The authors show HERV-K is associated with manifestations of bvFTD with TDP-43 pathology.