Mechanism of cooperative N-glycan processing by the multi-modular endoglycosidase EndoE
oleh: Mikel García-Alija, Jonathan J. Du, Izaskun Ordóñez, Asier Diz-Vallenilla, Alicia Moraleda-Montoya, Nazneen Sultana, Chau G. Huynh, Chao Li, Thomas Connor Donahue, Lai-Xi Wang, Beatriz Trastoy, Eric J. Sundberg, Marcelo E. Guerin
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-03-01 |
Deskripsi
EndoE is a multi-domain glycoside hydrolase of the human pathogen Enterococcus faecalis. Here, the authors present crystal structures of EndoE and provide biochemical insights into the molecular basis of EndoE’s substrate specificity and catalytic mechanism.