Capturing site-specific heterogeneity with large-scale N-glycoproteome analysis
oleh: Nicholas M. Riley, Alexander S. Hebert, Michael S. Westphall, Joshua J. Coon
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2019-03-01 |
Deskripsi
Mass spectrometry facilitates large-scale glycosylation profiling but in-depth analysis of intact glycopeptides is still challenging. Here, the authors show that activated ion electron transfer dissociation is suitable for glycopeptide fragmentation and improves glycoproteome coverage.