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Dense and accurate whole-chromosome haplotyping of individual genomes
oleh: David Porubsky, Shilpa Garg, Ashley D. Sanders, Jan O. Korbel, Victor Guryev, Peter M. Lansdorp, Tobias Marschall
Format: | Article |
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Diterbitkan: | Nature Portfolio 2017-11-01 |
Deskripsi
Haplotype information is important in investigating many biological phenomena. Here, Porubsky et al. combine Strand-seq with long-read or linked-read sequencing to obtain complete and genome-wide haplotypes of a single individual genome at manageable costs.