Genetic manipulation of the human gut bacterium Eggerthella lenta reveals a widespread family of transcriptional regulators

oleh: Xueyang Dong, Ben G. H. Guthrie, Margaret Alexander, Cecilia Noecker, Lorenzo Ramirez, Nathaniel R. Glasser, Peter J. Turnbaugh, Emily P. Balskus

Format: Article
Diterbitkan: Nature Portfolio 2022-12-01

Deskripsi

Eggerthella lenta is a prominent human gut bacterium implicated in several physiological processes, but its study has remained limited. Here, by developing a genetic toolbox for E. lenta, the authors provide insights into how the bacterium regulates drug and dietary compound metabolism.