Functional crosstalk between the cohesin loader and chromatin remodelers

oleh: Sofía Muñoz, Andrew Jones, Céline Bouchoux, Tegan Gilmore, Harshil Patel, Frank Uhlmann

Format: Article
Diterbitkan: Nature Portfolio 2022-12-01

Deskripsi

Chromatin remodelers direct the cohesin loader to nucleosome depleted regions where cohesin accesses chromosomes. Muñoz et al. now show that the cohesin loader in turn is a biochemical activator of a chromatin remodeler, helping to clear nucleosomes