Asymmetric division events promote variability in cell cycle duration in animal cells and Escherichia coli

oleh: Ulrich Berge, Daria Bochenek, Ralf Schnabel, Arne Wehling, Timm Schroeder, Tanja Stadler, Ruth Kroschewski

Format: Article
Diterbitkan: Nature Portfolio 2019-04-01

Deskripsi

We know that variations in cell cycle duration between cells naturally occur but the mechanisms are largely unknown. Here, using lineage tracking, hierarchical clustering and Monte Carlo methods, the authors show that large differences in granddaughter cell cycle duration are driven by asymmetric divisions.