Construction of a complete set of Neisseria meningitidis mutants and its use for the phenotypic profiling of this human pathogen
oleh: Alastair Muir, Ishwori Gurung, Ana Cehovin, Adelme Bazin, David Vallenet, Vladimir Pelicic
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2020-11-01 |
Deskripsi
The bacterium Neisseria meningitidis causes life-threatening meningitis and sepsis. Here, Muir et al. construct a complete collection of defined mutants in protein-coding genes of this organism, which they use to identify its essential genome and to shed light on the functions of multiple genes.