Sequence-to-function deep learning frameworks for engineered riboregulators
oleh: Jacqueline A. Valeri, Katherine M. Collins, Pradeep Ramesh, Miguel A. Alcantar, Bianca A. Lepe, Timothy K. Lu, Diogo M. Camacho
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2020-10-01 |
Deskripsi
The design of synthetic biology circuits remains challenging due to poorly understood design rules. Here the authors introduce STORM and NuSpeak, two deep-learning architectures to characterize and optimize toehold switches.